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UK Cilia Network


Dr Stephen Thorpe

Stephen Thorpe

Assistant Professor

School of Medicine
University College Dublin
ResearcherID ORCiD Google Scholar LinkedIn

Research Interests

mechanobiology, stem cells, cell mechanics, mechanotransduction, biomechanics

The aim of my research is to leverage fundamental mechanobiology knowledge to direct cell behaviour through specific cell-matrix interactions and biophysical stimulation for regenerative medicine and to disrupt aberrant mechano-signalling in disease. I implement a range of engineering, biophysics and molecular biology techniques to probe cellular responses to biophysical signals. In addition to enhancing our understanding of cell mechanobiology, my research looks to leverage this understanding to develop cartilage and bone regenerative medicine strategies, and address the aberrant mechanobiology associated with one of the most lethal cancers, pancreatic ductal adenocarcinoma.