Prof Martin KnightBEng, MSc, PhD
Professor of Mechanobiology
Queen Mary University of London
+44 (0)20 7882 8868
primary cilia, inflammation, bone, cartilage, mechanosignalling
Martin Knight’s research examines the interplay between the structure and the function of primary cilia and implications for musculoskeletal disease aetiology. This has potential impact in the development of cilia therapies which modulate cilia signalling pathways. Part of this work involves the area of mechanobiology and mechanotransduction or how living cells and tissues ‘sense and respond’ to mechanical forces. This is essential for the health and functionality of many tissues and therefore has application in various medical therapies from tissue engineering and regenerative medicine to pharmaceuticals. Studies are examining primary cilia in a variety of tissues including articular cartilage, tendon, ovarian cancer and mesenchymal stem cells.
Knight Cilia Research Group:
- Dr Clare Thompson (QM-Emulate organs-on-chips Centre)
- Dr Joanne Nolan (CR UK / EPSRC Grant)
- Dr Stephan Verbruggen (Research Visitor)
PhD Students (Cilia related):
- Mr Huan Meng
- Ms Megan McFie
- Mr Dariel Terrazas
I am happy for individuals outside my research group (particularly early career researchers) to present at one of my (online) group meetings – please contact me if you are interested.
Cilia Research Projects
The following are funded research projects related to cilia research.
Funding source: MRC / Value: £401,057Dates: September 2014 - March 2020
Funding source: CRUK and EPSRC / Value: £268,700Dates: December 2020 - May 2023