Programme
International Conference on Cilia, Flagella and Centrosomes
Co-organized by the French (GDR CIL) and UK Cilia Networks
Wednesday 27th November 2019
| 12:00am | Conference registration |
| 2:00pm | Welcome from the Organising committee: Sylvie Schneider-Maunoury, Barbara Tanos. |
| 2:15pm | Keynote lecture: Paul GUICHARD ( Geneva, Switzerland) The molecular architecture of the centriole |
| Session 1: Cilia and centrosome | |
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Chairs: Lukas CAJANEK and Peter SATIR |
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| 3:05pm | Imène BOUHLEL (Cambridge, UK): How is the centriole duplication site defined? |
| 3:25pm | Elif-Nur FIRAT-KARALAR (Istanbul, Turkey): Centriolar satellite integrity and distribution are required for efficient assembly and function of centrosomes and cilia |
| 3:45pm | Francesc GARCIA-GONZALO (Madrid, Spain): The c-terminal tails of htr6 and sstr3 contain ciliary localization sequences that act redundantly with those in the ic3 loop |
| 4:05pm | Coffee break Poster sessions 1 and 2 (odd numbers only) |
| 5:25pm | Swadhin Chandra JANA (Lisbon, Portugal): Cytoskeleton organising centre is essential for the homeostasis of the ciliated cell in Drosophila |
| 5:45pm | Jean-André LAPART (Lyon, France): DZIP1 and FAM92 form a ciliary transition zone module with cell type specific roles in Drosophila |
| 6:05pm | Megan McFIE (London, UK): High throughput confocal screen of 1,728 compounds to uncover novel regulators of chondrocyte cilia expression. |
| 6:25pm | Jung- Chi LIAO (Taipei, Taiwan): Super-resolution microscopy reveals coupling between mammalian centriole subdistal appendages and distal appendages |
| 6:45pm | Setting up of the "Networking Game" |
| 7:00pm | Welcome cocktail and Networking Game |
Thursday 28th November 2019
| 9:00am | Keynote lecture: Nathalie Jurisch-Yaksi (Trondheim, Norway): The function of motile cilia in ventricular flow and brain development |
| Session 2: Motile cilia and flagella | |
| Chairs: Juliette AZIMZADEH and Søren CHRISTENSEN | |
| 9:50am | Vito MENNELLA (Southampton, UK): Super-resolution Molecular Map of Basal Foot Reveals Novel Cilium in Airway Multiciliated Cells. |
| 10:10am | Olivier MERCEY (Paris, France): Revisiting the dynamic of multiple basal body production in Multiciliated Cells. |
| 10:30am | Coffee break Poster sessions 1 and 2 (even numbers only) |
| 11:50am | Anne-Marie TASSIN (Gif-sur-Yvette, France): MKS-NPHP module proteins control ciliary shedding at the transition zone |
| 12:10pm | Aminata TOURE (Paris, France): Mutations in TTC29, encoding an evolutionary conserved axonemal protein, result in asthenozoospermia and male infertility |
| 12:30pm | Buffet lunch |
| 1:30pm | Keynote lecture: Gaspar Jekely (Exeter, UK): Large-scale neuronal coordination of locomotor cilia |
| Session 3: Cilia and IFT in signaling and development | |
| Chairs: Dominic NORRIS and Nathalie SPASSKY | |
| 2:20pm | Isabelle CAILLE (Paris, France): Primary cilium cyclicamp regulates neuronal migration at the centrosome. |
| 2:40pm | Maximilien FURTHAUER (Nice, France): The circular fluid flow in the zebrafish left-right organizer ensures leftward particle transport. |
| 3:00pm | Sara PESTANA (Lisbon, Portugal): The Extracellular Vesicles in the Left-Right Organizer. |
| 3:20pm | Coffee break Poster sessions 3 and 4 (odd numbers only) |
| 4:40pm | Thomas THEIL (Edinburgh, UK): The Joubert gene INPP5E acts as a negative regulator of Sonic Hedgehog signaling in human brain organoids. |
| 5:00pm | Julien VERMOT (London, UK): Intraflagellar transport complex B proteins regulate the Hippo effector Yap1 during proepicardium development. |
| 5:20pm | Christine VESQUE (Paris, France): Searching for the initial triggers of scoliosis in the zebrafish rpgrip1l ciliopathy mutant |
| 5:40pm | Community meeting (Chairs: Hannah Mitchison, Philippe Bastin, Bénédicte Durand & Martin Knight). |
| 7:30pm | Gala dinner and/or pub |
Friday 29th November 2019
| Session 4: Ciliopathies: clinical aspects and molecular mechanisms. | |
| Chairs: Colin JOHNSON and Sophie SAUNIER | |
| 9:00am | Sebastian PATZKE (Oslo, Norway): A CEP104-CSPP1 complex is required for formation of primary cilia competent in Hedgehog signalling |
| 9:20am | Séverine BAR (Strasbourg, France): Mutations in CEMIP2 cause a ciliopathy by interfering with the control of primary cilium length at the centriolar satellites. |
| 9:40am | Sabrina MECHAUSSIER (Paris, France): Expanding the clinical spectrum associated with TUBB4B mutations. |
| 10:00am | Martina HURANOVA (Prague, Czech Republic): BBS1, BBS4 and BBS9 control the spatiotemporal assembly of the BBSome |
| 10:20am | Stefaan VERBRUGGEN (London, UK): Osteocyte primary cilia regulate breast cancer cell metastasic phenotype. |
| 10:40am | Coffee break Poster sessions 3 and 4 (even numbers only) |
| 12:00pm | Oliver BLACQUE (Dublin, Ireland): Ciliary RAB-28 regulates extracellular vesicle production and outer segment disk shedding, and is trafficked to cilia via a BBSome-ARL6-PDE6D pathway. |
| 12:20pm | Keynote lecture: Brunella Franco (Naples, Italy): OFD type I syndrome: lessons learned from a rare ciliopathy |
| 1:10pm | Closing remarks and awards (Philippe Bastin, Hannah Mitchison, Evi Goggolidou). |