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Research Projects

The various groups within the UK Cilia Network are engaged in numerous research projects investigating primary and motile cilia, and related structures and their role in development, ageing, health and disease. Many of these projects are collaborations between members of the network and funded through a variety of sources.

The following are current cilia-related projects funded by the Research Councils UK amounting to approximately £16M of live grants:

  • £467,824, Mar 19 - Mar 22
    Functional interplay of ciliary trafficking complexes and motor proteins.
    BBSRC award to University of Bristol and David John Stephens 

  • £252,065, Feb 19 - Jan 23
    Dynein-2: Building and maintaining a functional primary cilium
    BBSRC award to Birkbeck College and Anthony John Roberts 

  • £836,421, Feb 19 - Jan 23
    The role of dynein-2 in building a functional cilium.
    BBSRC award to University of Bristol and David John Stephens 

  • £448,520, Jan 19 - Dec 21
    Dissecting the molecular organisation of Fat-Dachsous cadherin complexes to understand mechanisms of coordinated cell polarisation
    BBSRC award to University of Sheffield and David Ian Strutt 

  • £400,339, Jan 19 - Dec 21
    How do the cadherins Fat and Dachsous control polarised cell behaviours during development?
    BBSRC award to University of Sheffield and David Ian Strutt 

  • £428,356, Dec 18 - Nov 21
    Building a molecular machine: analysis of co-chaperones for assembly of ciliary dynein motor complexes
    BBSRC award to University of Edinburgh and Andrew Jarman 

  • £487,528, Oct 18 - Sep 21
    Elicitor release upon flagellin glycan modification
    BBSRC award to University of Oxford and Renier Van Der Hoorn 

  • £494,135, Aug 18 - Jul 21
    A live model to study mucociliary clearance in health and disease
    NC3Rs award to University of Manchester and David Thornton 

  • £394,732, Dec 17 - Dec 20
    CILIA MEDIATED MECHANISM OF OTOLITH MINERALIZATION
    BBSRC award to University of Sheffield and Fredericus Johannes Van Eeden 

  • £444,059, Nov 17 - Oct 20
    Unravelling the molecular mechanisms controlling respiratory tract mucus gel formation in health and disease
    MRC award to University of Manchester and David Thornton 

  • £346,960, Jun 17 - Dec 20
    Dissecting the Molecular Mechanism of Intraflagellar Transport Motors
    BBSRC award to Birkbeck College and Anthony John Roberts 

  • £215,335, Apr 17 - Mar 20
    The Establishment of Left-Right Asymmetry in Mammalian Development
    NC3Rs award to University of Cambridge and David Andrew Turner 

  • £445,636, Apr 17 - Mar 20
    BBSome trafficking: investigating a novel pathway associated with virulence in Leishmania
    MRC award to Keele University and Helen Price 

  • £327,411, Apr 17 - Mar 21
    Bilateral BBSRC-SFI: Structure-function relationships in the ciliary transition zone
    BBSRC award to University of Leeds and Colin Anfimov Johnson 

  • £454,266, Nov 16 - Nov 19
    Control of stem cell proliferation and differentiation by primary cilia in the developing cerebral cortex
    BBSRC award to University of Edinburgh and Thomas Theil 

  • £589,399, Jan 16 - Dec 19
    PHOSPHOINOSITIDES IN CILIA FUNCTION AND CILIOPATHIES
    MRC award to University of Sheffield and Fredericus Johannes Van Eeden 

  • £416,779, Oct 15 - Sep 19
    The role of ciliary Ca2+ signalling in the regulation of intraflagellar transport
    BBSRC award to Marine Biological Association and Glen Wheeler 

  • £472,200, Feb 15 - Aug 19
    Using SBEM and cellular electron tomography to study the basal body/pro-basal body linker.
    BBSRC award to Oxford Brookes University and Sue Vaughan 

  • £401,057, Sep 14 - Mar 20
    Osteoarthrtis may be treated as an environmental ciliopathy
    MRC award to Queen Mary, University of London and Martin Matthew Knight 

  • £212,983, Jun 14 - Dec 18
    Evaluating genetic therapeutics in ciliopathies
    MRC award to University College London and Elizabeth Forsythe 

  • £1,630,787, Oct 12 -
    Core - Structure and Assembly Mechanisms of Centrioles
    MRC award to MRC Laboratory of Molecular Biology and Mark Van Breugel 

  • £4,729,850, Apr 97 -
    Cilia Development & Disease
    MRC award to MRC Mammalian Genetics Unit and Dominic Norris 

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